Kam Leong

Institution: Duke University
Address:

1395 CIEMAS

Office Phone: (919) 660-8466
kam.leong@duke.edu
http://fds.duke.edu/db/pratt/BME/faculty/kam.leong

Description

 

Professor Leong's research interest focuses on biomaterials design, particularly for synthesis of nanoparticles for gene and immunotherapy, and nanofibers for regenerative medicine applications.

Biomaterials Design:

  • design of self-assembled fibers for tissue engineering
  • synthesis of new biodegradable polymers and new polyelectrolytes for drug and gene delivery applied to tissue engineering
  • synthesis of thermosensitive hydrogels for tissue engineering

Controlled Drug and Gene Delivery:

  • oral gene delivery for hemophilia A and B
  • non-viral gene delivery to the GI tract, bladder, and CNS
  • oral delivery of antigen genes for vaccination

Tissue Engineering:

  • study of interaction of stem cells with biofunctional polymeric surface
  • expansion of hematopoietic stem cells
  • nerve guidance channels with drug and gene delivery functions
  • microencapsulation of stem cells and genetically-engineered cells
  • development of bioartificial nucleus pulposus device
  • study of interaction of SMC and neuronal stem cells with synthetic nanostructured biomaterials

 

Research Interests

Leong's research interest focuses on biomaterials design, particularly for synthesis of nanoparticles for gene and immunotherapy, and nanofibers for regenerative medicine applications.