The quantity of information on nanomaterial properties and behavior continues to grow exponentially. Without a concerted effort to organize and mine disparate information coming out of current research efforts, the value and effective use of this information will be limited at best. At worst, erroneous conclusions will be drawn and data will not be translated to knowledge. Nanoinformatics inherently supports a community-based approach to filter the noise and enhance the value of global information in nanoscience and nanotechnology.